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Abbott, Janssen, Pharmacyclics in Diagnostics Pact

To develop FISH-based test to identify high-risk CLL patients

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Abbott will collaborate with Janssen Biotech and Pharmacyclics to explore Abbott’s FISH (Fluorescence In Situ Hybridization) technology for the development of a molecular companion diagnostic test to identify patients with a genetic subtype of chronic lymphocytic leukemia (CLL), the most common form of adult leukemia.   Abbott will develop a FISH-based test to identify high-risk CLL patients that may respond to ibrutinib, an oral, small molecule inhibitor currently in development by Jansse...

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